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Antioxidant properties / No toxicity / Safety
Cancer / Transport / Delivery
Life extension / Rheumatoid arthritis / Air toxicity / Ischemia / Atherosclerosis
Osteoporosis / Thrombosis / Diabetes / Heart attack
Parkinson and Alzheimer
Various positive properties
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Research
Antioxidant properties / No toxicity / Safety
Highly hydroxylated or gamma-cyclodextrin-bicapped water-soluble derivative of fullerene: the antioxidant ability assessed by electron spin resonance method and beta-carotene bleaching assay
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Effects of fullerenol C60(OH)24 on the frequency of micronuclei and chromosome aberrations in CHO-K1 cells
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Fullerenol C60(OH)24 prevents doxorubicin-induced acute cardiotoxicity in rats
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Effect of fullerenol C(60)(OH) (24) on lipid peroxidation of kidneys, testes and lungs in rats treated with doxorubicine
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Concentration-dependent effects of fullerenol on cultured hippocampal neuron viability
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Gene expression and biochemical responses in brain of zebrafish Danio rerio exposed to organic nanomaterials: carbon nanotubes (SWCNT) and fullerenol (C60(OH)18-22(OK4))
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Fullerenol nanoparticles: toxicity and antioxidant activity
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Effects of fullerenol nanoparticles on acetamiprid induced cytoxicity and genotoxicity in cultured human lung fibroblasts
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On mechanism of antioxidant effect of fullerenols
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Bioluminescent Enzymatic Assay as a Tool for Studying Antioxidant Activity and Toxicity of Bioactive Compounds
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Mechanism of ROS scavenging and antioxidant signalling by redox metallic and fullerene nanomaterials: Potential implications in ROS associated degenerative disorders
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Effects of Fullerenols on Mouse Brain Microvascular Endothelial Cells
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Toxicity of functionalized fullerene and fullerene synthesis chemicals
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In vitro and in vivo study of the toxicity of fullerenols С 60, С 70 and С 120 О obtained by an original two step method
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The neuroprotective effect of fullerenols on a model of Parkinson’s disease in Drosophila melanogaster
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Antioxidant Activity and Toxicity of Fullerenols via Bioluminescence Signaling: Role of Oxygen Substituents
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Antioxidant activity of highly hydroxylated fullerene C60 and its interactions with the analogue of α-tocopherol
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The Puzzling Potential of Carbon Nanomaterials: General Properties, Application, and Toxicity
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Effect of fullerenol nanoparticles on oxidative stress induced by paraquat in honey bees
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Effects of fullerenol nanoparticles on kidney tissue in sevoflurane‑treated rats
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The Effect of Fullerenol C60(OH)36 on the Antioxidant Defense System in Erythrocytes
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Fullerenol nanoparticles prevents doxorubicin-induced acute hepatotoxicity in rats
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Mechanisms of Antioxidant Activities of Fullerenols from First-Principles Calculation
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Impact of Titanium Dioxide and Fullerenol Nanoparticles on Caco-2 Gut Epithelial Cells
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Fullerene-based antioxidants and neurodegenerative disorders
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Cancer / Transport / Delivery
Hepatoprotective effect of fullerenol/doxorubicin nanocomposite in acute treatment of healthy rats
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Exploring the Inhibitory and Antioxidant Effects of Fullerene and Fullerenol on Ribonuclease A
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Investigation of fullerenol-induced changes in poroelasticity of human hepatocellular carcinoma by AFM-based creep tests
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Nucleosome-inspired nanocarrier obtains encapsulation efficiency enhancement and side effects reduction in chemotherapy by using fullerenol assembled with doxorubicin
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Mono-fullerenols modulating cell stiffness by perturbing actin bundling
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Identification differential behavior of Gd@C 82(OH) 22 upon interaction with serum albumin using spectroscopic analysis
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Study of morphological and mechanical features of multinuclear and mononuclear SW480 cells by atomic force microscopy
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Aspartic acid derivatized hydroxylated fullerenes as drug delivery vehicles for docetaxel: an explorative study
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Injectable Fullerenol/Alginate Hydrogel for Suppression of Oxidative Stress Damage in Brown Adipose-Derived Stem Cells and Cardiac Repair
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Fullerenol-Based Intracellular Delivery of Methotrexate: A Water-Soluble Nanoconjugate for Enhanced Cytotoxicity and Improved Pharmacokinetics
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Fullerenol inhibits the cross-talk between bone marrow-derived mesenchymal stem cells and tumor cells by regulating MAPK signaling
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Investigation of fullerenol-induced changes in poroelasticity of human hepatocellular carcinoma by AFM-based creep tests
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Cardiac autonomic modulation induced by doxorubicin in a rodent model of colorectal cancer and the influence of fullerenol pretreatment
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Metallofullerenol Inhibits Cellular Iron Uptake by Inducing Transferrin Tetramerization
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Molecular mechanism of Gd@C 82(OH) 22 increasing collagen expression: Implication for encaging tumor
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Study of morphological and mechanical features of multinuclear and mononuclear SW480 cells by atomic force microscopy
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Aspartic acid derivatized hydroxylated fullerenes as drug delivery vehicles for docetaxel: an explorative study
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Biocompatible [60]/[70] Fullerenols: Potent Defense against Oxidative Injury Induced by Reduplicative Chemotherapy
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Hydrophobic Patch of Ubiquitin is Important for its Optimal Activation by Ubiquitin Activating Enzyme E1
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Fullerenol/doxorubicin nanocomposite mitigates acute oxidative stress and modulates apoptosis in myocardial tissue
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Fullerenols in therapy and diagnosis of cancer
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Fullerenes and their derivatives as inhibitors of tumor necrosis factor-α with highly promoted affinities
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Polyhydroxylated fullerenols regulate macrophage for cancer adoptive immunotherapy and greatly inhibit the tumor metastasis
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AFM-based study of fullerenol (C60(OH)24)-induced changes of elasticity in living SMCC-7721 cells
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Caging cancer
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Polyhydroxylated metallofullerenols stimulate IL-1β secretion of macrophage through TLRs/MyD88/NF-κB pathway and NLRP₃ inflammasome activation
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Modification of antioxidative and antiapoptotic genes expression in irradiated K562 cells upon fullerenol C60(OH)24 nanoparticle treatment
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Epigenetic modulation of human breast cancer by metallofullerenol nanoparticles: in vivo treatment and in vitro analysis
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Antioxidant properties of fullerenol C60(OH)24 in rat kidneys, testes, and lungs treated with doxorubicin
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Fullerenol-cytotoxic conjugates for cancer chemotherapy
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Protective effects of fullerenol C60(OH)24 against doxorubicin-induced cardiotoxicity and hepatotoxicity in rats with colorectal cancer
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Acute doxorubicin pulmotoxicity in rats with malignant neoplasm is effectively treated with fullerenol C60(OH)24 through inhibition of oxidative stress
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Cardioprotective effects of fullerenol C(60)(Oh)(24) on a single dose doxorubicin-induced cardiotoxicity in rats with malignant neoplasm
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Fullerenol C60(OH)24 effects on antioxidative enzymes activity in irradiated human erythroleukemia cell line
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Small size fullerenol nanoparticles suppress lung metastasis of breast cancer cell by disrupting actin dynamics
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Monitoring of Low-Intensity Exposures via Luminescent Bioassays of Different Complexity: Cells, Enzyme Reactions, and Fluorescent Proteins
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Characterization and Cytotoxicity of Polyprenol Lipid and Vitamin E-TPGS Hybrid Nanoparticles for Betulinic Acid and Low-Substituted Hydroxyl Fullerenol in MHCC97H and L02 Cells
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A Multiparametric Study of Internalization of Fullerenol C 60(OH) 36 Nanoparticles into Peripheral Blood Mononuclear Cells: Cytotoxicity in Oxidative Stress Induced by Ionizing Radiation
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Water-Soluble Fullerenol with Hydroxyl Group Dependence for Efficient Two-Photon Excited Photodynamic Inactivation of Infectious Microbes
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Biological and biocompatible characteristics of fullerenols nanomaterials for tissue engineering
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Life extension / Rheumatoid arthritis / Air toxicity / Ischemia / Atherosclerosis
Metallofullerene nanoparticles promote osteogenic differentiation of bone marrow stromal cells through BMP signaling pathway
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Evaluation of the influence of fullerenol on aging and stress resistance using Caenorhabditis elegans
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Anti-aging effect of fullerenol on skin aging through derived stem cells in a mouse model
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The prolongation of the lifespan of rats by repeated oral administration of [60]fullerene
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Evaluation of the influence of fullerenol on aging and stress resistance using Caenorhabditis elegans
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Charging nanoparticles: increased binding of Gd@C 82(OH) 22 derivatives to human MMP-9
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The antihyperlipidemic effects of fullerenol nanoparticles via adjusting the gut microbiota in vivo
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Fullerenol Nanoparticles Decrease Blood-Brain Barrier Interruption and Brain Edema during Cerebral Ischemia-Reperfusion Injury Probably by Reduction of Interleukin-6 and Matrix Metalloproteinase-9 Tra
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Characterization of fullerenol-protein interactions and an extended investigation on cytotoxicity
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Amelioration of Experimentally Induced Arthritis by Reducing Reactive Oxygen Species Production through the Intra-Articular Injection of Water-Soluble Fullerenol
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Fullerol nanoparticles suppress inflammatory response and adipogenesis of vertebral bone marrow stromal cells–A potential novel treatment for intervertebral disc degeneration
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Osteoporosis / Thrombosis / Diabetes / Heart attack
Modulated podosome patterning in osteoclasts by fullerenol nanoparticles disturbs the bone resorption for osteoporosis treatment
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Intrinsic Biotaxi Solution Based on Blood Cell Membrane Cloaking Enables Fullerenol Thrombolysis In Vivo
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Influence of fullerenol on hIAPP aggregation: amyloid inhibition and mechanistic aspects
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Interaction Principle Between Coagulation Factor X and Fullerene Derivatives with Different Hydrophilic-Hydrophobic Properties for Anticoagulation
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Small size fullerenol nanoparticles inhibit thrombosis and blood coagulation through inhibiting activities of thrombin and FXa
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Highly Dispersed Fullerenols Hamper Osteoclast Ruffled Border Formation by Perturbing Ca 2+ Bundles Osteoporosis, a common and serious bone disorder affecting aged people and postmenopausal women, is characterized by osteoclast overactivity. One therapeu
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Fullerenol nanoparticles suppress RANKL-induced osteoclastogenesis by inhibiting differentiation and maturation
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Axisymmetric Contact Problem for a Flattened Cell: Contributions of Substrate Effect and Cell Thickness to the Determination of Viscoelastic Properties by Using AFM Indentation
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Fullerenols and glucosamine fullerenes reduce infarct volume and cerebral inflammation after ischemic stroke in normotensive and hypertensive rats
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Parkinson and Alzheimer
Amphiphilic surface chemistry of fullerenols is necessary for inhibiting the amyloid aggregation of alpha-synuclein NACore
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Distinct Binding Dynamics, Sites and Interactions of Fullerene and Fullerenols with Amyloid-β Peptides Revealed by Molecular Dynamics Simulations
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Preferential binding of fullerene and fullerenol with the N-terminal and middle regions of amyloid beta peptide: an in silico investigation
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Fullerenol nanoparticles decrease ischaemia-induced brain injury and oedema through inhibition of oxidative damage and aquaporin-1 expression in ischaemic stroke
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Fullerenol C60(OH)16 prevents amyloid fibrillization of Aβ40-in vitro and in silico approach
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The neuroprotective effect of fullerenols on a model of Parkinson’s disease in Drosophila melanogaster
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Various positive properties
Fullerenol protects cornea from ultraviolet B exposure
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Long-term maintenance of synaptic plasticity by Fullerenol Ameliorates lead-induced-impaired learning and memory in vivo
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The transcriptome profile of RPE cells by the fullerenol against hydrogen peroxide stress
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Toxicity and Antioxidant Activity of Fullerenol C60,70 with Low Number of Oxygen Substituents
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Impacts of fullerene derivatives on regulating the structure and assembly of collagen molecules
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Exploiting the physicochemical properties of dendritic polymers for environmental and biological applications
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Fullerenol – properties and applications in biomedical sciences
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Fluorescence analysis of the action of soluble derivatives of fullerene C60 on amyloid fibrils of the brain peptide Abeta(1-42)
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INHIBITORY POTENTIAL OF POLYHYDROXYLATED FULLERENES AGAINST PROTEIN TYROSINE PHOSPHATASE 1B
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Fullerenol Nanoparticles Eradicate Helicobacter pylori via pH-Responsive Peroxidase Activity
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Fullerenol as a photoelectrochemical nanoprobe for discrimination and ultrasensitive detection of amplification-free single-stranded DNA
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Novel Mixed Matrix Sodium Alginate-Fullerenol Membranes: Development, Characterization, and Study in Pervaporation Dehydration of Isopropanol
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Two-Photon Photoexcited Photodynamic Therapy with Water-Soluble Fullerenol Serving as the Highly Effective Two-Photon Photosensitizer Against Multidrug-Resistant Bacteria
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Bioaccumulation, biodistribution,and depuration of 13 C-labelled fullerenols in zebrafish through dietary exposure
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Electrochemiluminescent Detection of Proteins Based on Fullerenols Modified Gold Nanoparticles and Triple Amplification Approaches
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Visualization of the tissue distribution of fullerenols in zebrafish (Danio rerio) using imaging mass spectrometry
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The mechanisms of action of water-soluble aminohexanoic and malonic adducts of fullerene C 60 with hexamethonium on model lipid membranes
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Dynamic Surface Properties of Fullerenol Solutions
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Molecular Semiconductor Surfactants with Fullerenol Heads and Colored Tails for Carbon Dioxide Photoconversion
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Fullerene-Directed Synthesis of Flowerlike Cu 3(PO 4) 2 Crystals for Efficient Photocatalytic Degradation of Dyes
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Fullerenol C 60(OH) 36 protects human erythrocyte membrane against high-energy electrons
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Increasing the Resistance of Living Cells against Oxidative Stress by Nonnatural Surfactants as Membrane Guards
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Inhalable gadofullerenol/[70] fullerenol as high-efficiency ROS scavengers for pulmonary fibrosis therapy
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Novel green PVA-fullerenol mixed matrix supported membranes for separating water-THF mixtures by pervaporation
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Fullerenols Revisited: Highly Monodispersed Photoluminescent Nanomaterials as Ideal Building Blocks for Supramolecular Chemistry
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Development and Characterization of New Pervaporation PVA Membranes for the Dehydration Using Bulk and Surface Modifications
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Enhancement of nano titanium dioxide coatings by fullerene and polyhydroxy fullerene in the photocatalytic degradation of the herbicide mesotrione
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Palladium-Catalyzed Reaction of [60]Fullerene with Aroyl Compounds via Enolate-Mediated sp 2 C-H Bond Activation and Hydroxylation
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Fullerenol C60(OH)24 increases ion permeability of lipid membranes in a pH-dependent manner
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Self-assembling, reactivity and molecular dynamics of fullerenol nanoparticles
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Carbon nanomaterials: Biologically active fullerene derivatives
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Investigation of work of adhesion of biological cell (human hepatocellular carcinoma) by AFM nanoindentation
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Synthesis and Characterization of Hydroxyapatite/Fullerenol Nanocomposites
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The influence of distribution of hydroxyl groups on vibrational spectra of fullerenol C60(OH)24 isomers: DFT study
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Fullerenol protects retinal pigment epithelial cells from oxidative stress-induced premature senescence via activating SIRT1
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Fullerenol C₆₀(OH)₃₆ could associate to band 3 protein of human erythrocyte membranes
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Morphologically virus-like fullerenol nanoparticles act as the dual-functional nanoadjuvant for HIV-1 vaccine
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Fullerenols as a new therapeutic approach in nanomedicine
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Comparative study of the interaction of fullerenol nanoparticles with eukaryotic and bacterial model membranes using solid-state NMR and FTIR spectroscopy
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Inhibition of sebum production and Propionibacterium acnes lipase activity by fullerenol, a novel polyhydroxylated fullerene: potential as a therapeutic reagent for acne
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Suitability of polyelectrolyte shells modified with fullerene derivate for immunoisolation of cells. Experimental study
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Polyhydroxy fullerenes (fullerols or fullerenols): beneficial effects on growth and lifespan in diverse biological models
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Super-highly hydroxylated fullerene derivative protects human keratinocytes from UV-induced cell injuries together with the decreases in intracellular ROS generation and DNA damages
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Antimicrobial activity of fullerenes and their hydroxylated derivatives
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Polyhydroxylated C60 fullerene (fullerenol) attenuates neutrophilic lung inflammation in mice
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Acute doxorubicin nephrotoxicity in rats with malignant neoplasm can be successfully treated with fullerenol C60(OH)24 via suppression of oxidative stress
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Dendrimer-Fullerenol Soft-Condensed Nanoassembly
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Production and consumption of reactive oxygen species by fullerenes
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Mechanism of taq DNA polymerase inhibition by fullerene derivatives: insight from computer simulations
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Production of monoclonal antibodies against fullerene C60 and development of a fullerene enzyme immunoassay
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The structural studies of fullerenol C60(OH)24 and nitric oxide mixture in water solvent – MD simulation
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The properties of small fullerenol cluster (C60(OH)24)7: computer simulation
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Nonlinear conductivity of fullerenol aqueous solutions
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Influences of the size and hydroxyl number of fullerenes/fullerenols on their interactions with proteins
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Facile synthesis of isomerically pure fullerenols and formation of spherical aggregates from C60(OH)8
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Light-initiated transformations of fullerenol in aqueous media
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Isothermal titration calorimetry study of the interaction of sweeteners with fullerenols as an artificial sweet taste receptor model
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1,4-Fullerenols C60ArOH: synthesis and functionalization
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Gd@C 82 Fullerenol
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Effects of hydroxyl group distribution on the reactivity, stability and optical properties of fullerenols
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Interaction of fullerenol with lysozyme investigated by experimental and computational approaches
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Determination of trace alkaline phosphatase by solid-substrate room-temperature phosphorimetry based on Triticum vulgare lectin labeled with fullerenol
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Facile synthesis of highly water-soluble fullerenes more than half-covered by hydroxyl groups
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Effect of fullerenol nanoparticles on oxidative stress induced by paraquat in honey bees
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Amelioration of Experimentally Induced Arthritis by Reducing Reactive Oxygen Species Production through the Intra-Articular Injection of Water-Soluble Fullerenol
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The neuroprotective effect of fullerenols on a model of Parkinson’s disease in Drosophila melanogaster
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Oxidation-induced water-solubilization and chemical functionalization of fullerenes C60, Gd@C60 and Gd@C82: atomistic insights into the formation mechanisms and structures of fullerenols synthesized by different methods
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Effect of fullerenol surface chemistry on nanoparticle binding-induced protein misfolding
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Polyhydroxylated fullerene attenuates oxidative stress-induced apoptosis via a fortifying Nrf2-regulated cellular antioxidant defence system Various positive properties
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The polyhydroxylated fullerene derivative C60(OH)24 protects mice from ionizing-radiation-induced immune and mitochondrial dysfunction
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